Anticancer Properties of an Important Drug Lead Podophyllotoxin Can Be Efficiently Mimicked by Diverse Heterocyclic Scaffolds Accessible via One-Step Synthesis-Reference-Cited by-同舟云学术

Anticancer Properties of an Important Drug Lead Podophyllotoxin Can Be Efficiently Mimicked by Diverse Heterocyclic Scaffolds Accessible via One-Step Synthesis

Published:2011-05-26 Issue:12 Volume:54 Page:4234-4246
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Magedov Igor V.,Frolova Liliya,Manpadi Madhuri,Bhoga Uma devi¹,Tang Hong,Evdokimov Nikolai M.,George Olivia²,Hadje Georgiou Kathy¹,Renner Steffen³,Getlik Matthäus⁴,Kinnibrugh Tiffany L.,Fernandes Manuel A.¹,Van slambrouck Severine,Steelant Wim F. A.,Shuster Charles B.²,Rogelj Snezna,van Otterlo Willem A. L.¹⁵,Kornienko Alexander

Affiliation:

1. Molecular Sciences Institute, School of Chemistry, University of the Witwatersrand, PO Wits, 2050 Johannesburg, South Africa

2. Department of Biology, New Mexico State University, Las Cruces, New Mexico 88003, United States

3. Max Planck Institute for Molecular Physiology, Dortmund, Germany

4. Chemical Genomics Centre of the Max Planck Society, Dortmund, Germany

5. Department of Chemistry and Polymer Sciences, Stellenbosch University, Stellenbosch 7600, Western Cape, South Africa

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm200410r