Discovery of Novel <i>N</i>-Heterocyclic-Fused Deoxypodophyllotoxin Analogues as Tubulin Polymerization Inhibitors Targeting the Colchicine-Binding Site for Cancer Treatment-Reference-Cited by-同舟云学术

Discovery of Novel N-Heterocyclic-Fused Deoxypodophyllotoxin Analogues as Tubulin Polymerization Inhibitors Targeting the Colchicine-Binding Site for Cancer Treatment

Published:2022-12-06 Issue:24 Volume:65 Page:16774-16800
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Leng Jiafu¹,Zhao Yongjun¹,Sheng Ping¹,Xia Yuanzheng¹,Chen Tingting¹,Zhao Shifang¹,Xie Shanshan¹,Yan Xiangyu¹,Wang Xiaobing¹^ORCID,Yin Yong¹^ORCID,Kong Lingyi¹^ORCID

Affiliation:

1. Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, People’s Republic of China

Funder

State Administration of Foreign Experts Affairs

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Higher Education Discipline Innovation Project

Double First-Class University Project

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c01595