The evolving role of natural products in drug discovery
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd1657.pdf
Reference111 articles.
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2. Projan, S. J. Infectious diseases in the 21st century: increasing threats, fewer new treatments and a premium on prevention. Cur. Opin. Pharmacol. 3, 457–458 (2003).
3. Kirsop, B. E. The convention on biological diversity: some implications for microbiology and microbial collections. J. Indust. Microbiol. Biotech. 17, 505–511 (1996).
4. Projan S. J. Why is big pharma getting out of antibacterial drug discovery? Curr. Opin. Microbiol. 6, 427–430 (2003).
5. Ajay, W. P. W. & Murcko, M. Can we learn to distinguish between 'Drug-Like' and 'Nondrug-like' molecules? J. Med. Chem. 41, 3314–3324 (1998).
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