Mediating K+/H+ Transport on Organelle Membranes to Selectively Eradicate Cancer Stem Cells with a Small Molecule-Reference-Cited by-同舟云学术

Mediating K+/H+ Transport on Organelle Membranes to Selectively Eradicate Cancer Stem Cells with a Small Molecule

Published:2020-05-22 Issue:24 Volume:142 Page:10769-10779
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Shen Fang-Fang¹,Dai Sheng-Yao¹,Wong Nai-Kei¹²,Deng Shan¹³,Wong Alice Sze-Tsai³^ORCID,Yang Dan¹^ORCID

Affiliation:

1. Morningside Laboratory for Chemical Biology, Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China

2. Department of Infectious Diseases, Shenzhen Third People’s Hospital, The Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen 518112, China

3. School of Biological Sciences, The University of Hong Kong, Pokfulam Road, Hong Kong, China

Funder

Research Grants Council, University Grants Committee

University of Hong Kong

Morningside Foundation

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.0c02134

Reference70 articles.

1. Principles of Selective Ion Transport in Channels and Pumps

2. Small-molecule ion channels increase host defences in cystic fibrosis airway epithelia

3. Restored iron transport by a small molecule promotes absorption and hemoglobinization in animals

4. Efficient, non-toxic anion transport by synthetic carriers in cells and epithelia

5. A small synthetic molecule functions as a chloride–bicarbonate dual-transporter and induces chloride secretion in cells

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