Design, Synthesis, and Evaluation of pH-Dependent Hydrolyzable Emetine Analogues as Treatment for Prostate Cancer-Reference-Cited by-同舟云学术

Design, Synthesis, and Evaluation of pH-Dependent Hydrolyzable Emetine Analogues as Treatment for Prostate Cancer

Published:2012-08-16 Issue:17 Volume:55 Page:7450-7459
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Akinboye Emmanuel S.¹,Rosen Marc D.²,Denmeade Samuel R.²,Kwabi-Addo Bernard³,Bakare Oladapo¹

Affiliation:

1. Department of Chemistry, Howard University, 525 College Street NW, Washington, D.C. 20059, United States

2. The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21239, United States

3. Department of Biochemistry and Cancer Center, Howard University, Washington, D.C. 20059, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm300426q

Reference37 articles.

1. Cancer Statistics, 2001

2. Cancer Statistics, 2010

3. The Emetine Alkaloids

4. STRUCTURAL BASIS FOR INHIBITION OF PROTEIN SYNTHESIS BY EMETINE AND CYCLOHEXIMIDE BASED ON AN ANALOGY BETWEEN IPECAC ALKALOIDS AND GLUTARIMIDE ANTIBIOTICS

Cited by 27 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Dual action anti‐inflammatory/antiviral isoquinoline alkaloids as potent naturally occurring anti‐SARS‐CoV‐2 agents: A combined pharmacological and medicinal chemistry perspective;Phytotherapy Research;2023-04-11

2. Discovery of Prodrug of MRTX1133 as an Oral Therapy for Cancers with KRAS^G12D Mutation;ACS Omega;2023-02-09

3. Efficient and Scalable Asymmetric Total Synthesis of (−)-Emetine with Pharmaceutical Grade Quality; First Multigram Scale Synthesis;Organic Process Research & Development;2023-01-24

4. Alkaloids as potential anticancer agent;Recent Frontiers of Phytochemicals;2023

5. Sustained release of alpha‐methylacyl‐CoA racemase (AMACR) antibody‐conjugated and free doxorubicin from silica nanoparticles for prostate cancer cell growth inhibition;Journal of Biomedical Materials Research Part B: Applied Biomaterials;2022-10-31