Fungal P450 Deconstructs the 2,5-Diazabicyclo[2.2.2]octane Ring <i>En Route</i> to the Complete Biosynthesis of 21<i>R</i>-Citrinadin A-Reference-Cited by-同舟云学术

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Fungal P450 Deconstructs the 2,5-Diazabicyclo[2.2.2]octane Ring En Route to the Complete Biosynthesis of 21R-Citrinadin A

Published:2023-06-23 Issue:26 Volume:145 Page:14251-14259
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Liu Shuai¹,Nie Qiuyue¹,Liu Zhiwen¹,Patil Siddhant¹,Gao Xue¹²³^ORCID

Affiliation:

1. Department of Chemical and Biomolecular Engineering, Rice University, Houston, Texas 77005, United States

2. Department of Bioengineering, Rice University, Houston, Texas 77005, United States

3. Department of Chemistry, Rice University, Houston, Texas 77005, United States

Funder

Welch Foundation

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.3c02109

Reference51 articles.

1. Structural and stereochemical diversity in prenylated indole alkaloids containing the bicyclo[2.2.2]diazaoctane ring system from marine and terrestrial fungi

2. Total synthesis and isolation of citrinalin and cyclopiamine congeners

3. Genome-Based Characterization of Two Prenylation Steps in the Assembly of the Stephacidin and Notoamide Anticancer Agents in a Marine-Derived Aspergillus sp.

4. Biochemical Characterization of NotB as an FAD-Dependent Oxidase in the Biosynthesis of Notoamide Indole Alkaloids

5. Notoamides A–D: Prenylated Indole Alkaloids Isolated from a Marine-Derived Fungus,Aspergillus sp.

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