1. Life Sciences Institute and Departments of Medicinal Chemistry, Microbiology & Immunology, and Chemistry, University of Michigan, Ann Arbor, Michigan 48109, Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, USA and University of Colorado Cancer Center, Aurora, Colorado 80045, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto 862...