2-Aryloxy-4-alkylaminopyridines: Discovery of Novel Corticotropin-Releasing Factor 1 Antagonists
Author:
Affiliation:
1. Medicinal Chemistry, Neuroscience, and Drug Metabolism Departments, PGRD, Pfizer, Inc., Groton, Connecticut 06340
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm070579c
Reference20 articles.
1. Characterization of a 41-Residue Ovine Hypothalamic Peptide That Stimulates Secretion of Corticotropin and β-Endorphin
2. Synthesis and Oral Efficacy of a 4-(Butylethylamino)pyrrolo[2,3-d]pyrimidine: A Centrally Active Corticotropin-Releasing Factor1 Receptor Antagonist
3. CP-154,526: a potent and selective nonpeptide antagonist of corticotropin releasing factor receptors.
4. Antidepressant-like effects of CP-154,526, a selective CRF1 receptor antagonist
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