Synthesis and Oral Efficacy of a 4-(Butylethylamino)pyrrolo[2,3-d]pyrimidine: A Centrally Active Corticotropin-Releasing Factor1 Receptor Antagonist-Reference-Cited by-同舟云学术

Synthesis and Oral Efficacy of a 4-(Butylethylamino)pyrrolo[2,3-d]pyrimidine: A Centrally Active Corticotropin-Releasing Factor1 Receptor Antagonist

Published:1997-05-01 Issue:11 Volume:40 Page:1749-1754
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Chen Yuhpyng L.¹,Mansbach Robert S.¹,Winter Steven M.¹,Brooks Elizabeth¹,Collins Judith¹,Corman Michael L.¹,Dunaiskis Audrey R.¹,Faraci W. Stephen¹,Gallaschun Randall J.¹,Schmidt Anne¹,Schulz David W.¹

Affiliation:

1. Medicinal Chemistry and Neuroscience Departments, Central Research Division, Pfizer Inc., Groton, Connecticut 06340

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm960861b

Reference20 articles.

1. Characterization of a 41-Residue Ovine Hypothalamic Peptide That Stimulates Secretion of Corticotropin and β-Endorphin

2. Cloning and functional expression of a rat brain corticotropin releasing factor (CRF) receptor.

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