Development of In Silico Models for Predicting Potential Time-Dependent Inhibitors of Cytochrome P450 3A4-Reference-Cited by-同舟云学术

Development of In Silico Models for Predicting Potential Time-Dependent Inhibitors of Cytochrome P450 3A4

Published:2022-12-02 Issue:1 Volume:20 Page:194-205
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Xu Minjie¹,Lu Zhou¹,Wu Zengrui¹^ORCID,Gui Minyan¹,Liu Guixia¹^ORCID,Tang Yun¹^ORCID,Li Weihua¹^ORCID

Affiliation:

1. Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai200237, China

Funder

Ministry of Science and Technology of the People's Republic of China

Shanghai Municipal Education Commission

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.2c00571

Reference72 articles.

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3. Studies─Cytochrome, I. V. D. I. P450 Enzyme-and Transporter-Mediated Drug Interactions Guidance for Industry. Center for Drug Evaluation and Research, US Department of Health and Human Services Food and Drug Administration: Silver Spring, MD, USA2020, pp 1–43.

4. U.S. FDA Approved Drugs from 2015–June 2020: A Perspective

5. Prevalence and Risk of Potential Cytochrome P450–Mediated Drug-Drug Interactions in Older Hospitalized Patients with Polypharmacy

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