Survey of Human Oxidoreductases and Cytochrome P450 Enzymes Involved in the Metabolism of Xenobiotic and Natural Chemicals

Author:

Rendic Slobodan1,Guengerich F. Peter2

Affiliation:

1. University of Zagreb, Haulikova 6, HR 1000 Zagreb, Croatia

2. Department of Biochemistry and Center in Molecular Toxicology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146, United States

Funder

National Institute of Environmental Health Sciences

National Cancer Institute

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Reference12 articles.

1. Contributions of Human Enzymes in Carcinogen Metabolism

2. Summary of information on human CYP enzymes: human P450 metabolism data

3. Human Cytochrome P450 Enzymes: A Status Report Summarizing Their Reactions, Substrates, Inducers, and Inhibitors

4. ADME Database: WEB Searchable ADME Database of Substrates, Inhibitors, Inducers and Activators of Cytochrome P450, Other Enzymes and Drug Transporters, Fujitsu Kyushu System Ltd., Fukuoka, Japan,http://jp.fujitsu.com/group/kyushu/en/services/admedatabase/.

5. DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS

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