Deep Learning Models Compared to Experimental Variability for the Prediction of CYP3A4 Time-Dependent Inhibition
Author:
Affiliation:
1. Novartis Biomedical Research, Novartis Campus, CH-4002 Basel, Switzerland
Funder
Novartis
Publisher
American Chemical Society (ACS)
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.3c00305
Reference47 articles.
1. Cytochrome P450 and Chemical Toxicology
2. Mechanism-based inactivation of CYP450 enzymes: a case study of lapatinib
3. Physicochemical Properties, Biotransformation, and Transport Pathways of Established and Newly Approved Medications: A Systematic Review of the Top 200 Most Prescribed Drugs vs. the FDA-Approved Drugs Between 2005 and 2016
4. Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation
5. Computational Models for Predicting Interactions with Cytochrome p450 Enzyme
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