Approaches to Understanding the Solution-State Organization of Spray-Dried Dispersion Feed Solutions and Its Translation to the Solid State-Reference-Cited by-同舟云学术

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Approaches to Understanding the Solution-State Organization of Spray-Dried Dispersion Feed Solutions and Its Translation to the Solid State

Published:2020-09-23 Issue:12 Volume:17 Page:4548-4563
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Defrese Matthew K.¹^ORCID,Farmer Matthew A.²,Long Yuhan³,Timmerman Lucas R.³,Bae Younsoo¹,Marsac Patrick J.¹

Affiliation:

1. Department of Pharmaceutical Sciences, University of Kentucky, Lexington, Kentucky 40506, United States

2. Department of Chemistry, University of Kentucky, Lexington, Kentucky 40506, United States

3. Department of Chemical and Materials Engineering, University of Kentucky, Lexington, Kentucky 40506, United States

Funder

Pharmaceutical Research and Manufacturers of America Foundation

Center for Pharmaceutical Development

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.0c00729

Reference87 articles.

1. Amorphous solid dispersions and nanocrystal technologies for poorly water-soluble drug delivery – An update

2. Solubility advantage of amorphous pharmaceuticals: I. A thermodynamic analysis

3. Predicting the Solubility Advantage of Amorphous Pharmaceuticals: A Novel Thermodynamic Approach

4. Estimation of Drug–Polymer Miscibility and Solubility in Amorphous Solid Dispersions Using Experimentally Determined Interaction Parameters

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1. Gaining Insight into the Role of the Solvent during Spray Drying of Amorphous Solid Dispersions by Studying Evaporation Kinetics;Molecular Pharmaceutics;2022-04-01

2. Structured Development Approach for Amorphous Systems;Formulating Poorly Water Soluble Drugs;2022

3. Optimizing Solvent Selection and Processing Conditions to Generate High Bulk-Density, Co-Precipitated Amorphous Dispersions of Posaconazole;Pharmaceutics;2021-11-26

4. The underestimated contribution of the solvent to the phase behavior of highly drug loaded amorphous solid dispersions;International Journal of Pharmaceutics;2021-11

5. Solvent influence on manufacturability, phase behavior and morphology of amorphous solid dispersions prepared via bead coating;European Journal of Pharmaceutics and Biopharmaceutics;2021-10

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