Importance of Net Hydrophobicity in the Cellular Uptake of All-Hydrocarbon Stapled Peptides
Author:
Affiliation:
1. Institute for Chemical Research, Kyoto University, Uji, Kyoto 611-0011, Japan
Funder
Japan Society for the Promotion of Science
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.7b01130
Reference38 articles.
1. Structure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes
2. The Future of Peptide-based Drugs
3. Synthetic therapeutic peptides: science and market
4. Lactam-Stapled Cell-Penetrating Peptides: Cell Uptake and Membrane Binding Properties
5. Design of Triazole-Stapled BCL9 α-Helical Peptides to Target the β-Catenin/B-Cell CLL/lymphoma 9 (BCL9) Protein–Protein Interaction
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