In Situ Characterization of the Microstructural Evolution of Biopharmaceutical Solid-State Formulations with Implications for Protein Stability-Reference-Cited by-同舟云学术

In Situ Characterization of the Microstructural Evolution of Biopharmaceutical Solid-State Formulations with Implications for Protein Stability

Published:2018-11-28 Issue:1 Volume:16 Page:173-183
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Koshari Stijn H. S.¹^ORCID,Nayak Purnendu K.²,Burra Shalini²,Zarraga Isidro E.,Rajagopal Karthikan^ORCID,Liu Yun¹³^ORCID,Wagner Norman J.¹^ORCID,Lenhoff Abraham M.¹^ORCID

Affiliation:

1. Center for Molecular and Engineering Thermodynamics, Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware 19716, United States

2. Eurofins Lancaster Laboratories Inc., Lancaster, Pennsylvania 17605, United States

3. Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, United States

Funder

Genentech

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.8b00935

Reference31 articles.

1. Drying-Induced Variations in Physico-Chemical Properties of Amorphous Pharmaceuticals and Their Impact on Stability (I): Stability of a Monoclonal Antibody**Official contribution of NIST; not subject to copyright in the U.S. Certain commercial equipment, instruments, or materials are identified in this article in order to specify the experimental procedure adequately. Such identification is not intended to imply recommendation or endorsement by the National Institute of Standards and Technology, nor is it intended to imply that the materials or equipment identified are necessarily the best available for the purpose.