Long-Term Amorphous Drug Stability Predictions Using Easily Calculated, Predicted, and Measured Parameters-Reference-Cited by-同舟云学术

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Long-Term Amorphous Drug Stability Predictions Using Easily Calculated, Predicted, and Measured Parameters

Published:2015-08-12 Issue:9 Volume:12 Page:3389-3398
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Nurzyńska Katarzyna¹,Booth Jonathan²,Roberts Clive J.¹,McCabe James²,Dryden Ian³,Fischer Peter M.¹

Affiliation:

1. School of Pharmacy and Centre for Biomolecular Sciences, The University of Nottingham, Nottingham NG7 2RD, United Kingdom

2. Pharmaceutical Development, AstraZeneca, Macclesfield SK10 2NA, United Kingdom

3. School of Mathematical Sciences, The University of Nottingham, Nottingham NG7 2RD, United Kingdom

Funder

AstraZeneca

Engineering and Physical Sciences Research Council

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.5b00409

Reference36 articles.

1. Amorphous pharmaceutical solids: preparation, characterization and stabilization

2. Solid dispersions as strategy to improve oral bioavailability of poor water soluble drugs

3. Parallel screening approach to identify solubility-enhancing formulations for improved bioavailability of a poorly water-soluble compound using milligram quantities of material

4. Computational Prediction of Drug Solubility in Lipid Based Formulation Excipients

5. A decision-support tool for the formulation of orally active, poorly soluble compounds

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