Parallel screening approach to identify solubility-enhancing formulations for improved bioavailability of a poorly water-soluble compound using milligram quantities of material

Author:

Dai Wei-Guo,Dong Liang C.,Li Shu,Pollock-Dove Crystal,Chen Jing,Mansky Paul,Eichenbaum Gary

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference39 articles.

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3. A high-throughput screening method for the determination of aqueous drug solubility using laser nephelometry in microtiter plates;Bevan;Anal. Chem.,2000

4. Intravenous administration of poorly soluble new drug entities in early drug discovery: the potential impact of formulation on pharmacokinetic parameters;Bittner;Curr. Opin. Drug Discov. Dev.,2002

5. Bysouth, S.R., Hite, S.W., Nettleton-Hammond, J.H., Bergstrom, K.I., Bohara, A., Landham, R.R., Lukkari, I.G., 2005. Preparation and characterization of formulations in a high throughput mode (USA). US 2005058574, 30 pp.

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