Antibody–Drug Conjugates (ADCs) Derived from Interchain Cysteine Cross-Linking Demonstrate Improved Homogeneity and Other Pharmacological Properties over Conventional Heterogeneous ADCs-Reference-Cited by-同舟云学术

Antibody–Drug Conjugates (ADCs) Derived from Interchain Cysteine Cross-Linking Demonstrate Improved Homogeneity and Other Pharmacological Properties over Conventional Heterogeneous ADCs

Published:2015-10-02 Issue:11 Volume:12 Page:3986-3998
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Behrens Christopher R.¹,Ha Edward H.¹,Chinn Lawrence L.¹,Bowers Simeon¹,Probst Gary¹,Fitch-Bruhns Maureen¹,Monteon Jorge¹,Valdiosera Amanda¹,Bermudez Abel¹,Liao-Chan Sindy¹,Wong Tiffany¹,Melnick Jonathan¹,Theunissen Jan-Willem¹,Flory Mark R.¹,Houser Derrick¹,Venstrom Kristy¹,Levashova Zoia¹,Sauer Paul¹,Migone Thi-Sau¹,van der Horst Edward H.¹,Halcomb Randall L.¹,Jackson David Y.¹

Affiliation:

1. Igenica Biotherapeutics, 863A Mitten Road, Suite 100B, Burlingame, California 94010, United States

Funder

U.S. Department of Health and Human Services

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.5b00432

Reference35 articles.

1. Antibody-drug conjugates