In Vitro and in Vivo Characterization of MOD-4023, a Long-Acting Carboxy-Terminal Peptide (CTP)-Modified Human Growth Hormone-Reference-Cited by-同舟云学术

In Vitro and in Vivo Characterization of MOD-4023, a Long-Acting Carboxy-Terminal Peptide (CTP)-Modified Human Growth Hormone

Published:2016-01-18 Issue:2 Volume:13 Page:631-639
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Hershkovitz Oren¹,Bar-Ilan Ahuva¹,Guy Rachel¹,Felikman Yana¹,Moschcovich Laura¹,Hwa Vivian²,Rosenfeld Ron G.³,Fima Eyal¹,Hart Gili¹

Affiliation:

1. OPKO Biologics, Nes Ziona 7414002, Israel

2. Division of Endocrinology, Cincinnati Center for Growth Disorders, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio 45229, United States

3. Department of Pediatrics, Oregon Health & Science University, Portland, Oregon 97239, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.5b00868

Reference21 articles.

1. American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for Growth Hormone Use in Growth Hormone-Deficient Adults and Transition Patients – 2009 Update

2. Optimizing GH Therapy in Adults and Children

3. Compliance and Persistence in Pediatric and Adult Patients Receiving Growth Hormone Therapy

4. Developments in human growth hormone preparations: sustained-release, prolonged half-life, novel injection devices, and alternative delivery routes

5. Status of long-acting-growth hormone preparations — 2015

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