Design, Synthesis, and Validation of a Branched Flexible Linker for Bioactive Peptides-Reference-Cited by-同舟云学术

Design, Synthesis, and Validation of a Branched Flexible Linker for Bioactive Peptides

Published:2007-02-06 Issue:5 Volume:72 Page:1675-1680
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Bowen Martina E.¹,Monguchi Yasunari¹,Sankaranarayanan Rajesh¹,Vagner Josef¹,Begay Lucinda J.¹,Xu Liping¹,Jagadish Bhumasamudram¹,Hruby Victor J.¹,Gillies Robert J.¹,Mash Eugene A.¹

Affiliation:

1. Department of Chemistry, University of Arizona, Tucson, Arizona 85721-0041, and Department of Biochemistry and Molecular Biophysics, The Arizona Cancer Center, Tucson, Arizona 85724-5024

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo062276g

Reference31 articles.

1. Meeting Report: High-Throughput Technologies for In Vivo Imaging Agents

2. Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors

3. Synthetic multivalent ligands in the exploration of cell-surface interactions

Cited by 18 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Developing a Biased Unmatched Bivalent Ligand (BUmBL) Design Strategy to Target the GPCR Homodimer Allosteric Signaling (cAMP over β-Arrestin 2 Recruitment) Within the Melanocortin Receptors;Journal of Medicinal Chemistry;2018-04-18

2. Bench-top to clinical therapies: A review of melanocortin ligands from 1954 to 2016;Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease;2017-10

3. A Direct in Vivo Comparison of the Melanocortin Monovalent Agonist Ac-His-DPhe-Arg-Trp-NH2 versus the Bivalent Agonist Ac-His-DPhe-Arg-Trp-PEDG20-His-DPhe-Arg-Trp-NH2: A Bivalent Advantage;ACS Chemical Neuroscience;2017-02-16

4. An in Vitro and in Vivo Investigation of Bivalent Ligands That Display Preferential Binding and Functional Activity for Different Melanocortin Receptor Homodimers;Journal of Medicinal Chemistry;2016-03-29

5. Synthesis and bioactivity of MSH4 oligomers prepared by an A2+ B2 strategy;Tetrahedron Letters;2015-06