SARS-CoV-2 Main Protease Drug Design, Assay Development, and Drug Resistance Studies
Author:
Affiliation:
1. Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, New Jersey 08854, United States
Funder
National Institute of Allergy and Infectious Diseases
Publisher
American Chemical Society (ACS)
Subject
General Medicine,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.accounts.2c00735
Reference52 articles.
1. Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease
2. Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M pro and cathepsin L
3. Expedited Approach toward the Rational Design of Noncovalent SARS-CoV-2 Main Protease Inhibitors
4. Discovery of Di- and Trihaloacetamides as Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity
5. Characteristics of SARS-CoV-2 and COVID-19
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