The Design, Synthesis, and Antiviral Activity of 4′-Azidocytidine Analogues against Hepatitis C Virus Replication: The Discovery of 4′-Azidoarabinocytidine-Reference-Cited by-同舟云学术

The Design, Synthesis, and Antiviral Activity of 4′-Azidocytidine Analogues against Hepatitis C Virus Replication: The Discovery of 4′-Azidoarabinocytidine

Published:2008-12-05 Issue:1 Volume:52 Page:219-223
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Smith David B.¹,Kalayanov Genadiy¹,Sund Christian¹,Winqvist Anna¹,Pinho Pedro¹,Maltseva Tatiana¹,Morisson Veronique¹,Leveque Vincent¹,Rajyaguru Sonal¹,Pogam Sophie Le¹,Najera Isabel¹,Benkestock Kurt¹,Zhou Xiao-Xiong¹,Maag Hans¹,Cammack Nick¹,Martin Joseph A.¹,Swallow Steven¹,Johansson Nils Gunnar¹,Klumpp Klaus¹,Smith Mark¹

Affiliation:

1. Roche Palo Alto LLC, 3431 Hillview Avenue, Palo Alto, California 94304, Medivir AB, Department of Medicinal Chemistry, Lunastigen 7, SE-141 44 Huddinge, Sweden

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm800981y

Reference14 articles.

1. Epidemiology of Hepatitis C: Geographic Differences and Temporal Trends

2. Peginterferon Alfa-2a plus Ribavirin for Chronic Hepatitis C Virus Infection

3. Synthesis and Pharmacokinetics of Valopicitabine (NM283), an Efficient Prodrug of the Potent Anti-HCV Agent 2‘-C-Methylcytidine

4. Design, Synthesis, and Antiviral Activity of 2‘-Deoxy-2‘-fluoro-2‘-C-methylcytidine, a Potent Inhibitor of Hepatitis C Virus Replication

5. Design, synthesis, and antiviral properties of 4′-substituted ribonucleosides as inhibitors of hepatitis C virus replication: The discovery of R1479

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