Synthesis and Pharmacokinetics of Valopicitabine (NM283), an Efficient Prodrug of the Potent Anti-HCV Agent 2‘-C-Methylcytidine-Reference-Cited by-同舟云学术

Synthesis and Pharmacokinetics of Valopicitabine (NM283), an Efficient Prodrug of the Potent Anti-HCV Agent 2‘-C-Methylcytidine

Published:2006-10-06 Issue:22 Volume:49 Page:6614-6620
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pierra Claire¹,Amador Agnès¹,Benzaria Samira¹,Cretton-Scott Erika¹,D'Amours Marc¹,Mao John¹,Mathieu Steven¹,Moussa Adel¹,Bridges Edward G.¹,Standring David N.¹,Sommadossi Jean-Pierre¹,Storer Richard¹,Gosselin Gilles¹

Affiliation:

1. Laboratoire Coopératif Idenix−CNRS−Université Montpellier II, Case Courrier 008, Université Montpellier II, Place Eugène Bataillon, 34095 Montpellier Cedex 5, France, and Idenix Pharmaceuticals Inc., 60 Hampshire Street, Cambridge, Massachusetts 02139, and Laboratoires Idenix SARL, Laboratoire de Chimie Médicinale, Cap Gamma, 1682 Rue de la Valsière, BP 50001, 34189 Montpellier Cedex 4, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0603623

Reference29 articles.

1. Chronic viral hepatitis

2. Challenges and successes in developing new therapies for hepatitis C

Cited by 181 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Discovery of C-Linked Nucleoside Analogues with Antiviral Activity against SARS-CoV-2;ACS Infectious Diseases;2024-04-23

2. Structure-Based Drug Design of RdRp Inhibitors against SARS-CoV-2;Topics in Current Chemistry;2023-06-15

3. Evaluation of 3D Human Intestinal Organoids as a Platform for EV-A71 Antiviral Drug Discovery;Cells;2023-04-12

4. Cationic Perylene Antivirals with Aqueous Solubility for Studies In Vivo;Pharmaceuticals;2022-09-22

5. Journey of remdesivir from the inhibition of hepatitis C virus to the treatment of COVID-19;Antiviral Therapy;2022-03-01