An Efficient, Regioselective Amination of 3,5-Disubstituted Pyridine N-Oxides Using Saccharin as an Ammonium Surrogate
Author:
Affiliation:
1. Chemical Process Research and Development, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol303218p
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2. Structure−Activity Relationship Study of Prion Inhibition by 2-Aminopyridine-3,5-dicarbonitrile-Based Compounds: Parallel Synthesis, Bioactivity, and in Vitro Pharmacokinetics
3. Novel pyrrolyl 2-aminopyridines as potent and selective human β-secretase (BACE1) inhibitors
4. Discovery of novel 2-aminopyridine-3-carboxamides as c-Met kinase inhibitors
5. A General and Efficient 2-Amination of Pyridines and Quinolines
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