Novel pyrrolyl 2-aminopyridines as potent and selective human β-secretase (BACE1) inhibitors-Reference-Cited by-同舟云学术

Novel pyrrolyl 2-aminopyridines as potent and selective human β-secretase (BACE1) inhibitors

Published:2010-04 Issue:7 Volume:20 Page:2068-2073
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Malamas Michael S.,Barnes Keith,Hui Yu,Johnson Matthew,Lovering Frank,Condon Jeff,Fobare William,Solvibile William,Turner Jim,Hu Yun,Manas Eric S.,Fan Kristi,Olland Andrea,Chopra Rajiv,Bard Jonathan,Pangalos Menelas N.,Reinhart Peter,Robichaud Albert J.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference20 articles.

1. Economics of dementia and pharmacoeconomics of dementia therapy

2. Alzheimer's disease as a disorder of mechanisms underlying structural brain self-organization

3. The Pathogenesis of Senile Plaques

4. Alzheimer's Disease--Genotypes, Phenotype, and Treatments

5. The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics

Cited by 44 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Interaction Analysis by Fragment Molecular Orbital Method for Drug Discovery Research;Chemical and Pharmaceutical Bulletin;2024-09-01

2. Synthesis of 2‐Aminopyridine Derivatives via a Tandem CuAAC/Ring‐Cleavage/[4+2]‐Cycloaddition/Rearrangement Reaction Sequence;Advanced Synthesis & Catalysis;2024-08-07

3. Multicolor, Cell-Impermeable, and High Affinity BACE1 Inhibitor Probes Enable Superior Endogenous Staining and Imaging of Single Molecules;Journal of Medicinal Chemistry;2024-06-06

4. Recent Advances in Computational Modeling of BACE1 Inhibitors as Anti-Alzheimer Agents;Neuromethods;2023

5. Applications of piperazine scaffold in drug design;Privileged Scaffolds in Drug Discovery;2023