Alzheimer's Disease--Genotypes, Phenotype, and Treatments-Reference-Cited by-同舟云学术

Alzheimer's Disease--Genotypes, Phenotype, and Treatments

Published:1997-01-31 Issue:5300 Volume:275 Page:630-631
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Selkoe Dennis J.¹

Affiliation:

1. The author is at the Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA 02115, USA.

Abstract

What causes Alzheimer's disease? Selkoe's Perspective reviews recent research identifying four different genetic causes of Alzheimer's disease and suggests that all four point toward the deposition of amyloid beta in the brain as the initial trigger for the disease.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference33 articles.

1. Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production

2. Release of Excess Amyloid β Protein from a Mutant Amyloid β Protein Precursor

3. Haass C. , Hung A. Y. , Selkoe D. J. , Teplow D. B., J. Biol. Chem. 269, 17741 (1994);

4. An Increased Percentage of Long Amyloid β Protein Secreted by Familial Amyloid β Protein Precursor (βApp 717 ) Mutants

5. Excessive production of amyloid beta-protein by peripheral cells of symptomatic and presymptomatic patients carrying the Swedish familial Alzheimer disease mutation.

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