Glass-Transition Temperature of the β-Relaxation as the Major Predictive Parameter for Recrystallization of Neat Amorphous Drugs
Author:
Affiliation:
1. Department of Pharmacy, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark
2. Department of Chemical Engineering and Biotechnology, University of Cambridge, Philippa Fawcett Drive, Cambridge, CB3 0AS, United Kingdom
Funder
Engineering and Physical Sciences Research Council
Publisher
American Chemical Society (ACS)
Subject
Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry
Link
http://pubs.acs.org/doi/pdf/10.1021/acs.jpcb.7b10105
Reference50 articles.
1. Physical stability of drugs after storage above and below the glass transition temperature: Relationship to glass-forming ability
2. Long-Term Amorphous Drug Stability Predictions Using Easily Calculated, Predicted, and Measured Parameters
3. Characteristics and Significance of the Amorphous State in Pharmaceutical Systems
4. Applying Thermodynamic and Kinetic Parameters to Predict the Physical Stability of Two Differently Prepared Amorphous Forms of Simvastatin
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