Bile acids with a cyclopropyl-containing side chain. 3. Separation, identification, and properties of all four stereoisomers of 3.alpha.,7.beta.-dihydroxy-22,23-methylene-5.beta.-cholan-24-oic acid-Reference-Cited by-同舟云学术

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Bile acids with a cyclopropyl-containing side chain. 3. Separation, identification, and properties of all four stereoisomers of 3.alpha.,7.beta.-dihydroxy-22,23-methylene-5.beta.-cholan-24-oic acid

Published:1988-04 Issue:4 Volume:31 Page:730-736
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pellicciari Roberto,Natalini Benedetto,Cecchetti Sergio,Porter Barry,Roda Aldo,Grigolo Brunella,Balducci Renzo

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm00399a007

Cited by 20 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Synthesis and biological activity of cyclopropyl Δ7-dafachronic acids as DAF-12 receptor ligands;Organic & Biomolecular Chemistry;2021

2. The Discovery of Obeticholic Acid (Ocaliva™): First-in-Class FXR Agonist;Successful Drug Discovery;2018-04-16

3. Bile Acid Derivatives as Ligands of the Farnesoid X Receptor: Molecular Determinants for Bile Acid Binding and Receptor Modulation;Current Topics in Medicinal Chemistry;2014-11-24

4. New Methodology toward α,β-Unsaturated Carboxylic Acids from Saturated Acids;Organic Letters;2014-02-19

5. Conformational properties of cholic acid, a lead compound at the crossroads of bile acid inspired drug discovery;Med. Chem. Commun.;2014

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