Macrocyclic Inhibitors of β-Secretase: Functional Activity in an Animal Model-Reference-Cited by-同舟云学术

Macrocyclic Inhibitors of β-Secretase: Functional Activity in an Animal Model

Published:2006-09-01 Issue:21 Volume:49 Page:6147-6150
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Stachel Shawn J.¹,Coburn Craig A.¹,Sankaranarayanan Sethu¹,Price Eric A.¹,Pietrak Beth L.¹,Huang Qian¹,Lineberger Janet¹,Espeseth Amy S.¹,Jin Lixia¹,Ellis Joan¹,Holloway M. Katharine¹,Munshi Sanjeev¹,Allison Timothy¹,Hazuda Daria¹,Simon Adam J.¹,Graham Samuel L.¹,Vacca Joseph P.¹

Affiliation:

1. Department of Medicinal Chemistry, Biological Chemistry, Molecular Systems and Structural Biology Merck Research Laboratories, Post Office Box 4, West Point, Pennsylvania 19486

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm060884i

Reference25 articles.

1. Translating cell biology into therapeutic advances in Alzheimer's disease

2. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

3. Protease inhibitors as potential disease-modifying therapeutics for Alzheimer’s disease

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