Using Matched Molecular Series as a Predictive Tool To Optimize Biological Activity
Author:
Affiliation:
1. NextMove Software, Cambridge, CB4 0EY, U.K.
2. AstraZeneca, Mölndal, SE-431 83, Sweden
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm500022q
Reference33 articles.
1. Matched Molecular Pairs as a Medicinal Chemistry Tool
2. Matched Molecular Pair Analysis in drug discovery
3. Matched Molecular Pairs as a Guide in the Optimization of Pharmaceutical Properties; a Study of Aqueous Solubility, Plasma Protein Binding and Oral Exposure
4. Large-scale exploration of bioisosteric replacements on the basis of matched molecular pairs
Cited by 52 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Discovery of IRAK4 Inhibitors BAY1834845 (Zabedosertib) and BAY1830839;Journal of Medicinal Chemistry;2024-01-17
2. Prospective Validation of Machine Learning Algorithms for Absorption, Distribution, Metabolism, and Excretion Prediction: An Industrial Perspective;Journal of Chemical Information and Modeling;2023-05-22
3. Matched Molecular Pair Analysis in Drug Discovery: Methods and Recent Applications;Journal of Medicinal Chemistry;2023-04-04
4. Discovery of Antitrypanosomal Indolylacetamides by a Deconstruction–Optimization Strategy Applied to Paullones;ChemMedChem;2023-03-28
5. Useful Computational Chemistry Tools for Medicinal Chemistry;The Handbook of Medicinal Chemistry;2023-02-03
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3