Tetramethylammonium Fluoride Tetrahydrate for SNAr Fluorination of 4-Chlorothiazoles at a Production Scale-Reference-Cited by-同舟云学术

Tetramethylammonium Fluoride Tetrahydrate for SNAr Fluorination of 4-Chlorothiazoles at a Production Scale

Published:2021-04-26 Issue:5 Volume:25 Page:1167-1175
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Hawk Mai Khanh¹,Ryan Sarah J.¹^ORCID,Zhang Xin²,Huang Ping²,Chen Jing²,Liu Chuanren²,Chen Jianping²,Lindsay-Scott Peter J.³^ORCID,Burnett John³,White Craig³,Lu Yu¹^ORCID,Rizzo John R.¹

Affiliation:

1. Small Molecule Design and Development (SMDD), Lilly Technology Center North, Eli Lilly and Company, 1400 W Raymond Street, Indianapolis, Indiana 46221, United States

2. STA Pharmaceutical (WuXi STA), A Subsidiary of WuXi AppTec., No. 7 Building, #90 Delin Rd, WaiGaoQiao Free Trade Zone, Shanghai 200131, People’s Republic of China

3. Eli Lilly and Company Limited, Erl Wood Manor, Windlesham, Surrey GU20 6PH, U.K.

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.1c00042

Reference49 articles.

1. Fluorine in Pharmaceuticals: Looking Beyond Intuition

2. Fluorine in medicinal chemistry

3. The unique role of halogen substituents in the design of modern agrochemicals

4. Applications of Fluorine in Medicinal Chemistry

5. Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review

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