Commercial Route Development Toward PF-07265807, an AXL-MER Inhibitor Oncology Candidate
Author:
Affiliation:
1. Pfizer R&D UK Ltd., Kent, Sandwich CT13 9NJ, U.K.
Publisher
American Chemical Society (ACS)
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.4c00049
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3. Abstract 1735: The potent and selective MERTK/AXL inhibitor PF-5807/ARRY-067 activates dendritic cells to cross-prime CD8+T cells for anti-tumor activity
4. Hinklin, R.; Allen, S.; Barbour, P.; Cook, A.; Dahlke, J.; Gaudino, J.; Laird, E.; McNulty, O.; Zhao, Q. Pyrazolo[3,4-b]pyridine Compounds as Inhibitors of TAM AND MET Kinases. Patent WO,2,020,047,184 A1, 2020.
5. Development and Scale-Up of a Continuous Manufacturing Process for a Hydrazine Condensation Reaction
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1. Early-Stage Flow Process Development of a Key Intermediate toward PF-07265807, an AXL-MER Inhibitor Oncology Candidate;Organic Process Research & Development;2024-07-31
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