Flow Chemistry and Continuous Processing: More Mainstream than Ever!-Reference-Cited by-同舟云学术

Flow Chemistry and Continuous Processing: More Mainstream than Ever!

Published:2024-05-17 Issue:5 Volume:28 Page:1269-1271
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Cole Kevin P.¹^ORCID,Jaworski Jonathan N.²^ORCID,Kappe C. Oliver³^ORCID,Kobayashi Shu⁴^ORCID,Maguire Anita R.⁵^ORCID,O’Kearney-McMullan Anne⁶,Pesti Jaan A.⁷

Affiliation:

1. Synthetic Molecule Design and Development, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, United States

2. Process Chemistry Development, Takeda Pharmaceuticals International Co., 35 Landsdowne Street, Cambridge, Massachusetts 02139, United States

3. Institute of Chemistry, University of Graz, Heinrichstrasse 28, A-8010 Graz, Austria

4. Department of Chemistry, School of Science, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

5. School of Chemistry and School of Pharmacy, Analytical and Biological Chemistry Research Facility, SSPC, the SFI Research Centre for Pharmaceuticals, University College Cork, Cork T12 K8AF, Ireland

6. Chemical Development, Pharmaceutical Technology & Development, Operations, AstraZeneca, Macclesfield SK10 2NA, United Kingdom

7. Pharma Resource Group Inc., 880 Enterprise Drive, Royersford, Pennsylvania 19468, United States

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.3c00483

Reference8 articles.

1. The Evolving State of Continuous Processing in Pharmaceutical API Manufacturing: A Survey of Pharmaceutical Companies and Contract Manufacturing Organizations

2. Q13 Continuous Manufacturing of Drug Substances and Drug Products: Guidance for Industry. U.S. Food and Drug Administration, March 2023. https://www.fda.gov/regulatory-information/search-fda-guidance-documents/q13-continuous-manufacturing-drug-substances-and-drug-products (accessed 2023-11-18).

3. Process Research for ZG1077, a KRAS G12C Inhibitor

4. Selective Metalation of Functionalized Quinazolines to Enable Discovery and Advancement of Covalent KRAS Inhibitors

5. Development of a Commercial Manufacturing Process for Sotorasib, a First-in-Class KRAS^G12C Inhibitor

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