Preparation of the HIV Attachment Inhibitor BMS-663068. Part 6. Friedel–Crafts Acylation/Hydrolysis and Amidation-Reference-Cited by-同舟云学术

Preparation of the HIV Attachment Inhibitor BMS-663068. Part 6. Friedel–Crafts Acylation/Hydrolysis and Amidation

Published:2017-08-09 Issue:8 Volume:21 Page:1145-1155
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Zheng Bin¹^ORCID,Silverman Steven M.¹,Steinhardt Sarah E.¹,Kolotuchin Sergei¹,Iyer Vidya¹,Fan Junying¹,Skliar Dimitri¹,McLeod Douglas D.¹,Bultman Michael¹,Tripp Jonathan C.¹,Murugesan Saravanababu¹,La Cruz Thomas E.¹^ORCID,Sweeney Jason T.¹,Eastgate Martin D.¹^ORCID,Conlon David A.¹

Affiliation:

1. Chemical & Synthetic Development, Bristol-Myers Squibb Company, One Squibb Drive, New Brunswick, New Jersey, 08903-0191, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.7b00133

Reference31 articles.

1. Synthesis of the 6-Azaindole Containing HIV-1 Attachment Inhibitor Pro-Drug, BMS-663068

2. Preparation of the HIV Attachment Inhibitor BMS-663068. Part 2. Strategic Selections in the Transition from an Enabling Route to a Commercial Synthesis

3. Preparation of the HIV Attachment Inhibitor BMS-663068. Part 5. Selective C-7 Bromination of the 6-Azaindole Core

4. Synthetic Process Development of BMS-599793 Including Azaindole Negishi Coupling on Kilogram Scale

5. bWang, T.; Zhang, Z.; Meanwell, N. A.; Kadow, J. F.; Yin, Z.; Xue, Q. M.; Regueiro-Ren, A.; Matiskella, J. D.; Ueda, Y.U.S. Patent A20040186292, 2004.For general references on amidations with CDI, see:

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