Preparation of the HIV Attachment Inhibitor BMS-663068. Part 2. Strategic Selections in the Transition from an Enabling Route to a Commercial Synthesis-Reference-Cited by-同舟云学术

Preparation of the HIV Attachment Inhibitor BMS-663068. Part 2. Strategic Selections in the Transition from an Enabling Route to a Commercial Synthesis

Published:2017-08-09 Issue:8 Volume:21 Page:1110-1121
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Chen Ke¹,Risatti Christina¹,Simpson James¹,Soumeillant Maxime¹,Soltani Michelle¹,Bultman Michael¹,Zheng Bin¹^ORCID,Mudryk Boguslaw¹,Tripp Jonathan C.¹,La Cruz Thomas E.¹^ORCID,Hsiao Yi¹,Conlon David A.¹,Eastgate Martin D.¹^ORCID

Affiliation:

1. Chemical & Synthetic Development, Bristol-Myers Squibb, One Squibb Drive, New Brunswick, New Jersey 08903, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.7b00121

Reference29 articles.

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2. bUeda, Y.; Connolly, T. P.; Kadow, J. F.; Meanwell, N. A.; Wang, T.; Chen, C-P. H.; Yeung, K.S.; Zhang, Z.; Leahy, D. K.; Pack, S. K.; Soundararajan, N.; Sirard, P.; Levesque, K.; Thoraval, D.US 2005/0209246, 2005.

3. https://www.viivhealthcare.com/our-medicines/medicines-in-development.aspx.

4. Synthesis of the 6-Azaindole Containing HIV-1 Attachment Inhibitor Pro-Drug, BMS-663068

5. bEastgate, M. D.; Bultman, M. S.; Chen, K.; Fanfair, D. D.; Fox, R. J.; La Cruz, T. E.; Mudryk, B. M.; Risatti, C. A.; Simpson, J. H.; Soumeillant, M. C.; Tripp, J. C.; Xiao, Y.US2013/0203992, 2013.

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