Facile and Scalable Methodology for the Pyrrolo[2,1-<i>f</i>][1,2,4]triazine of Remdesivir-Reference-Cited by-同舟云学术

Facile and Scalable Methodology for the Pyrrolo[2,1-f][1,2,4]triazine of Remdesivir

Published:2022-01-07 Issue:1 Volume:26 Page:82-90
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Roy Sarabindu¹,Yadaw Ajay¹,Roy Subho¹,Sirasani Gopal²,Gangu Aravind²,Brown Jack D.²,Armstrong Joseph D.²,Stringham Rodger W.³^ORCID,Gupton B. Frank³^ORCID,Senanayake Chris H.²,Snead David R.³^ORCID

Affiliation:

1. Kolkata - R&D Centre, TCG Lifesciences Private Limited, Chemistry, Block BN, Plot 7, Salt Lake Electronics Complex, Sector V, Kolkata, West Bengal 700091, India

2. TCG GreenChem, Inc., 737 North 5th Street, Suite 467, Richmond, Virginia 23219, United States

3. Medicines for All Institute, 737 N 5th Street, Box 980100, Richmond, Virginia 23298, United States

Funder

Bill and Melinda Gates Foundation

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.1c00071

Reference22 articles.

1. Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses