Highly Regioselective and Practical Synthesis of 5-Bromo-4-chloro-3-nitro-7-azaindole-Reference-Cited by-同舟云学术

Highly Regioselective and Practical Synthesis of 5-Bromo-4-chloro-3-nitro-7-azaindole

Published:2017-03-31 Issue:4 Volume:21 Page:664-668
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Han Chong¹^ORCID,Green Keena¹,Pfeifer Eugen²,Gosselin Francis¹

Affiliation:

1. Department of Small Molecule Process Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States

2. Department of Pharma Technical Development, F. Hoffmann-La Roche AG, Grenzacherstrasse 124, CH-4070 Basel, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.7b00060

Reference22 articles.

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2. The Azaindole Framework in the Design of Kinase Inhibitors

3. Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

4. ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

5. Blake, J. F.; Guanawardana, I. W.; Huerou, Y. L.; Mohr, P. J.; Wallace, E. M.; Wang, B.Pyrrolopyridines as Kinase Inhibitors. U.S. Patent 8,841,304, Sep 23, 2014.

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