Discovery of Pyrrolo[2,3-b]pyridine (1,7-Dideazapurine) Nucleoside Analogues as Anti-Trypanosoma cruzi Agents-Reference-Cited by-同舟云学术

Discovery of Pyrrolo[2,3-b]pyridine (1,7-Dideazapurine) Nucleoside Analogues as Anti-Trypanosoma cruzi Agents

Published:2019-09-08 Issue:19 Volume:62 Page:8847-8865
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lin Cai¹,Hulpia Fabian¹,da Silva Cristiane França²,Batista Denise da Gama Jaen²,Van Hecke Kristof³^ORCID,Maes Louis⁴,Caljon Guy⁴,Soeiro Maria de Nazaré C.²,Van Calenbergh Serge¹^ORCID

Affiliation:

1. Laboratory for Medicinal Chemistry (Campus Heymans), Ghent University, Ottergemsesteenweg 460, B-9000 Gent, Belgium

2. Laboratório de Biologia Celular, Instituto Oswaldo Cruz (FIOCRUZ), Fundação Oswaldo Cruz, Rio de Janeiro, Avenida Brasil 4365, Manguinhos, 21040-360 Rio de Janeiro, Brazil

3. XStruct, Department of Chemistry, Ghent University, Krijgslaan 281 S3, B-9000 Gent, Belgium

4. Laboratory of Microbiology, Parasitology and Hygiene, University of Antwerp, Universiteitsplein 1 (S7), B-2610 Wilrijk, Belgium

Funder

Herculesstichting

Universiteit Antwerpen

Fonds Wetenschappelijk Onderzoek

China Scholarship Council

Bijzonder Onderzoeksfonds

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b01275

Reference34 articles.

1. Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need

2. Challenges and recent progress in drug discovery for tropical diseases

3. Chagas disease: A Latin American health problem becoming a world health problem

4. Chagas disease

5. Current drug therapy and pharmaceutical challenges for Chagas disease

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