Photochemistry in Pharmaceutical Development: A Survey of Strategies and Approaches to Industry-wide Implementation

Author:

Moschetta Eric G.1ORCID,Cook Gemma C.2ORCID,Edwards Lee J.3ORCID,Ischay Michael A.4ORCID,Lei Zhen5ORCID,Buono Frederic5ORCID,Lévesque François6ORCID,Garber Jeffrey A. O.7ORCID,MacTaggart Maura8,Sezen-Edmonds Melda8ORCID,Cole Kevin P.9ORCID,Beaver Matthew G.10ORCID,Doerfler Jaika11ORCID,Opalka Suzanne M.12ORCID,Liang Wenli12,Morse Peter D.13,Miyake Naomi14

Affiliation:

1. Small Molecule CMC Development, Process Engineering, AbbVie, Inc., 1401 Sheridan Road, North Chicago, Illinois 60064, United States

2. Discovery High-Throughput Chemistry, GSK, Gunnels Wood Road, Stevenage SG1 2NY, U.K.

3. Drug Substance Development, Process Engineering, GSK, Gunnels Wood Road, Stevenage SG1 2NY, U.K.

4. Process Chemistry, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, California 94404, United States

5. Chemical Development US, Boehringer Ingelheim Pharmaceuticals, Inc., 900 Ridgebury Road, Ridgefield, Connecticut 06877, United States

6. Process Research & Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States

7. Process Development, Gilead Alberta ULC, 1021 Hayter Road NW, Edmonton, Alberta T6S 1A1, Canada

8. Chemical Process Development, Bristol Myers Squibb, 1 Squibb Drive, New Brunswick, New Jersey 08903, United States

9. Synthetic Molecule Design and Development, Eli Lilly and Company, Indianapolis, Indiana 46285, United States

10. Drug Substance Technologies − Synthetics, Amgen, 360 Binney Street, Cambridge, Massachusetts 02410, United States

11. Drug Substance Technologies − Synthetics, Amgen, One Amgen Center Drive, Thousand Oaks, California 91320, United States

12. Chemical Process Development, Biogen, 225 Binney Street, Cambridge, Massachusetts 02142, United States

13. Chemical Research & Development, Pfizer Worldwide Research & Development, Groton, Connecticut 06340, United States

14. CMC Synthetics, Sanofi, 350 Water Street, Cambridge, Massachusetts 02141, United States

Publisher

American Chemical Society (ACS)

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