Expanding the Medicinal Chemist Toolbox: Comparing Seven C(sp2)–C(sp3) Cross-Coupling Methods by Library Synthesis-Reference-Cited by-同舟云学术

Expanding the Medicinal Chemist Toolbox: Comparing Seven C(sp2)–C(sp3) Cross-Coupling Methods by Library Synthesis

Published:2020-03-23 Issue:4 Volume:11 Page:597-604
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Dombrowski Amanda W.¹^ORCID,Gesmundo Nathan J.¹,Aguirre Ana L.¹,Sarris Katerina A.¹,Young Jonathon M.¹,Bogdan Andrew R.¹^ORCID,Martin M. Cynthia²,Gedeon Shasline³,Wang Ying¹^ORCID

Affiliation:

1. AbbVie, Inc., 1 North Waukegan Road, North Chicago, Illinois 60064, United States

2. Northwestern University Center for Molecular Innovation and Drug Discovery, 2145 Sheridan Road, Evanston, Illinois 60208, United States

3. Florida A&M University College of Pharmacy and Pharmaceutical Sciences, 1415 South Martin Luther King, Jr. Boulevard, Tallahassee, Florida 32307, United States

Funder

U.S. Department of Education

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.0c00093

Reference38 articles.

1. Expanding the medicinal chemistry synthetic toolbox

2. Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?

3. The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates