Scale-Up Synthesis of 1-Methyladamantane and Its Functionalization as a Key Point for Promising Antiviral Agents-Reference-Cited by-同舟云学术

Scale-Up Synthesis of 1-Methyladamantane and Its Functionalization as a Key Point for Promising Antiviral Agents

Published:2023-02-24 Issue:3 Volume:27 Page:477-487
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Pashenko Alexander E.¹²³,Gaidai Alexandr¹³⁴,Hryhoriev Nazar¹⁴,Volovenko Olesia¹,Levandovskiy Igor⁴,Maksymenko Olga¹,Volochnyuk Dmitriy M.¹²³^ORCID,Ryabukhin Sergey V.¹²³^ORCID

Affiliation:

1. Enamine Ltd., 78 Chervonotkatska Street, 02660 Kyiv, Ukraine

2. Taras Shevchenko National University of Kyiv, 60 Volodymyrska Street, 01033 Kyiv, Ukraine

3. Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska Street, 02660 Kyiv, Ukraine

4. National Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”, 37 Peremohy Avenue, 03056 Kyiv, Ukraine

Funder

Enamine Ltd.

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.2c00305

Reference46 articles.

1. The Lipophilic Bullet Hits the Targets: Medicinal Chemistry of Adamantane Derivatives

2. 1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: A Potent, Selective, and Orally Bioavailable Dipeptidyl Peptidase IV Inhibitor with Antihyperglycemic Properties

3. Discovery and Preclinical Profile of Saxagliptin (BMS-477118): A Highly Potent, Long-Acting, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes

4. DPP-4 inhibitors and their potential role in the management of type 2 diabetes

5. Amantadine in the treatment of Parkinson's disease

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