1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: A Potent, Selective, and Orally Bioavailable Dipeptidyl Peptidase IV Inhibitor with Antihyperglycemic Properties-Reference-Cited by-同舟云学术

1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: A Potent, Selective, and Orally Bioavailable Dipeptidyl Peptidase IV Inhibitor with Antihyperglycemic Properties

Published:2003-05-24 Issue:13 Volume:46 Page:2774-2789
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Villhauer Edwin B.¹,Brinkman John A.¹,Naderi Goli B.¹,Burkey Bryan F.¹,Dunning Beth E.¹,Prasad Kapa¹,Mangold Bonnie L.¹,Russell Mary E.¹,Hughes Thomas E.¹

Affiliation:

1. Novartis Institute for Biomedical Research, One Health Plaza, East Hanover, New Jersey 07936

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm030091l

Reference84 articles.

1. Proline-Dependent Structural and Biological Properties of Peptides and Proteins

2. Dipeptidyl-peptidase IV (CD26)-role in the inactivation of regulatory peptides

3. Dipeptidyl-Peptidase IV-beta, a Novel form of Cell-Surface-Expressed Protein with Dipeptidyl-Peptidase IV Activity

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