Discovery and Preclinical Profile of Saxagliptin (BMS-477118): A Highly Potent, Long-Acting, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes-Reference-Cited by-同舟云学术

Discovery and Preclinical Profile of Saxagliptin (BMS-477118): A Highly Potent, Long-Acting, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes

Published:2005-06-24 Issue:15 Volume:48 Page:5025-5037
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Augeri David J.¹,Robl Jeffrey A.¹,Betebenner David A.¹,Magnin David R.¹,Khanna Ashish¹,Robertson James G.¹,Wang Aiying¹,Simpkins Ligaya M.¹,Taunk Prakash¹,Huang Qi¹,Han Song-Ping¹,Abboa-Offei Benoni¹,Cap Michael¹,Xin Li¹,Tao Li¹,Tozzo Effie¹,Welzel Gustav E.¹,Egan Donald M.¹,Marcinkeviciene Jovita¹,Chang Shu Y.¹,Biller Scott A.¹,Kirby Mark S.¹,Parker Rex A.¹,Hamann Lawrence G.¹

Affiliation:

1. Departments of Discovery Chemistry, Metabolic Diseases, Pharmaceutical Candidate Optimization, Exploratory Pharmaceutics, Chemical Enzymology, Bristol-Myers Squibb, Pharmaceutical Research Institute, P.O. Box 5400, Princeton, New Jersey 08543-5400

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm050261p

Reference64 articles.

1. Diabetes Mellitus: Pathogenesis and Treatment Strategies

2. Glucagon-like Peptide-1: The Basis of a New Class of Treatment for Type 2 Diabetes

Cited by 601 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. An efficient green synthesis and in vitro evaluation of novel adamantane-containing 4-thiazolidinone derivatives as anticancer agents;Journal of Molecular Structure;2025-02

2. Advanced technologies for screening and identifying covalent inhibitors;TrAC Trends in Analytical Chemistry;2024-09

3. Enantioselective One-Pot Synthesis of Cyclopropane-Fused Tetrahydroquinolines via a Ru-Catalyzed Intramolecular Cyclopropanation;Organic Letters;2024-07-24

4. A Comprehensive Review on Selective Catalytic Methods for Functionalization of Adamantane Scaffolds;Asian Journal of Organic Chemistry;2024-07-03

5. Design, Synthesis, and Acaricidal/Insecticidal Activities of New Phenylpyrazole Derivatives Comprising an Imide Moiety;Journal of Agricultural and Food Chemistry;2024-06-29