Merging Biocatalysis, Flow, and Surfactant Chemistry: Innovative Synthesis of an FXI (Factor XI) Inhibitor-Reference-Cited by-同舟云学术

Merging Biocatalysis, Flow, and Surfactant Chemistry: Innovative Synthesis of an FXI (Factor XI) Inhibitor

Published:2020-11-09 Issue:11 Volume:24 Page:2780-2788
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Wu Bin¹^ORCID,Zhang Sisi¹,Hong Tao¹,Zhou Yizong¹,Wang Hui¹,Shi Min¹,Yang Hongwei¹^ORCID,Tian Xiangguang¹,Guo Jing¹,Bian Jianwei¹,Roache James²^ORCID,Delgado Pete²,Mo Ruowei²,Fridrich Cary²,Gao Feng¹^ORCID,Wang Jianhua¹

Affiliation:

1. Chemical and Analytical Development, Suzhou Novartis Technical Development Co., Ltd., Changshu, Jiangsu 215537, P. R. China

2. Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Inc., Cambridge, Massachusetts 02139, United States

Funder

Novartis

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.0c00412

Reference23 articles.

1. Genetically Determined FXI (Factor XI) Levels and Risk of Stroke

2. Reduced incidence of ischemic stroke in patients with severe factor XI deficiency

3. Management and Outcomes of Bleeding Events in Patients in the Emergency Department Taking Warfarin or a Non–Vitamin K Antagonist Oral Anticoagulant

4. Andexanet Alfa for Acute Major Bleeding Associated with Factor Xa Inhibitors

5. Novel Oral Anticoagulants for Venous Thromboembolism with Special Emphasis on Risk of Hemorrhagic Complications and Reversal Agents

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