Conformation Analyses, Dynamic Behavior and Amide Bond Distortions of Medium-sized Heterocycles. 1. Partially and Fully Reduced 1-Benzazepines-Reference-Cited by-同舟云学术

Conformation Analyses, Dynamic Behavior and Amide Bond Distortions of Medium-sized Heterocycles. 1. Partially and Fully Reduced 1-Benzazepines

Published:2005-01-29 Issue:5 Volume:70 Page:1545-1551
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Qadir Maryiam¹,Cobb Jonathan¹,Sheldrake Peter W.¹,Whittall Neil¹,White Andrew J. P.¹,Hii King Kuok (Mimi)¹,Horton Peter N.¹,Hursthouse Michael B.¹

Affiliation:

1. Department of Chemistry, King's College London, Strand WC2R 2LS, U.K. GlaxoSmithKline, Old Powder Mills, Nr. Leigh, Tonbridge, Kent TN11 9AN, U.K. Department of Chemistry, Imperial College London, Exhibition Road, South Kensington SW7 2AZ, U.K., and EPSRC X-ray Crystallography Service, Southampton University, Highfield SO17 1BJ, U.K.

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo048118b

Reference16 articles.

1. Novel Design of Nonpeptide AVP V2 Receptor Agonists: Structural Requirements for an Agonist Having 1-(4-Aminobenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine as a Template

2. Nonpeptide Arginine Vasopressin Antagonists for Both V1A and V2 Receptors: Synthesis and Pharmacological Properties of 4'-(5-(Substituted Methylidene)-2,3,4,5-tetrahydro-1H-1-benzoazepine-1-carbonyl)benzanilide and 4'-(5-(Substituted Methyl)-2,3-dihydro-1H-1-benzoazepine-1-carbonyl)benzanilide Derivatives.

3. Characterization of Orally Active Nonpeptide Vasopressin V2 Receptor Agonist. Synthesis and Biological Evaluation of Both the (5R)- and (5S)-Enantioisomers of 2-[1-(2-Chloro-4-pyrrolidin-1-yl-benzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepin- 5-yl]-N-isopropylacetamide

4. 7-Chloro-5-hydroxy-1-[2-methyl-4-(2-methylbenzoylamino)benzoyl]-2,3,4,5-tetrahydro-1 H -1-benzazepine (OPC-41061): A potent, orally active nonpeptide arginine vasopressin V 2 receptor antagonist

5. Recent discovery and development of non-peptide vasopressin V2receptor agonists

Cited by 84 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A Nickel(II) Chloride and Tetrahydroxydiboron Cocatalyzed Facile Synthesis of Benzo[b]azepines with an Appended Fluorinated Side Chain;Synthesis;2023-05-22

2. Stereochemical Analysis of Trifluoroacetamide Derivatives Based on Through-Space ¹H–¹⁹F Spin–Spin Couplings;The Journal of Organic Chemistry;2023-05-18

3. Synthesis of Tetrahydroazepines through Silyl Aza-Prins Cyclization Mediated by Iron(III) Salts;The Journal of Organic Chemistry;2022-08-17

4. Regio- and Diastereoselective Construction of Functionalized Benzo[b]oxepines and Benzo[b]azepines via Recyclable Gold(I)-Catalyzed Cyclizations;The Journal of Organic Chemistry;2022-05-20

5. Iodine-Mediated Pyridine Ring Expansion for the Construction of Azepines;Organic Letters;2022-03-14