Characterization of Orally Active Nonpeptide Vasopressin V2 Receptor Agonist. Synthesis and Biological Evaluation of Both the (5R)- and (5S)-Enantioisomers of 2-[1-(2-Chloro-4-pyrrolidin-1-yl-benzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepin- 5-yl]-N-isopropylacetamide-Reference-Cited by-同舟云学术

Characterization of Orally Active Nonpeptide Vasopressin V2 Receptor Agonist. Synthesis and Biological Evaluation of Both the (5R)- and (5S)-Enantioisomers of 2-[1-(2-Chloro-4-pyrrolidin-1-yl-benzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepin- 5-yl]-N-isopropylacetamide

Published:2002-07-16 Issue:17 Volume:45 Page:3805-3808
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kondo Kazumi¹,Kan Keizo¹,Tanada Yoshihisa¹,Bando Masahiko¹,Shinohara Tomoichi¹,Kurimura Muneaki¹,Ogawa Hidenori¹,Nakamura Shigeki¹,Hirano Takahiro¹,Yamamura Yoshitaka¹,Kido Masaru¹,Mori Toyoki¹,Tominaga Michiaki¹

Affiliation:

1. Second Tokushima Institute of New Drug Research, Otsuka Pharmaceutical Company, 463-10 Kagasuno Kawauchi-cho, Tokushima 771-0192, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm020133q

Reference20 articles.

1. Characterization of the human liver vasopressin receptor. Profound differences between human and rat vasopressin-receptor-mediated responses suggest only a minor role for vasopressin in regulating human hepatic function

2. Voltage-dependent Ca2+ channel and Na+ channel in frog taste cells

3. Characterization of human platelet vasopressin receptors.

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