Occurrence and Minimization of Cysteine Racemization during Stepwise Solid-Phase Peptide Synthesis1,2

Author:

Han Yongxin1,Albericio Fernando1,Barany George1

Affiliation:

1. Department of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, and Department of Organic Chemistry, University of Barcelona, 08028-Barcelona, Spain

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Reference35 articles.

1. Present address:  Hybridon, Inc., 155 Fortune Blvd., Milford, MA 01757.

2. Reviews:  (a) Barany, G.; Merrifield, R. B. InThe Peptides;Gross, E., Meienhofer, J., Eds.; Academic Press:  New York, NY, 1979; Vol. 2, pp 1-284. (b) Atherton, E.; Sheppard, R. C.Solid Phase Peptide Synthesis:  A PracticalApproach;IRL Press:  Oxford, 1989. (c) Fields, G. B.; Tian, Z.; Barany, G. InSynthetic Peptides. A User's Guide; Grant, G. A., Ed.; W. H. Freeman and Co.  New York, 1992; pp 77−183. (d) Merrifield, B. InPeptides:  Synthesis,Structures, and Applications;Gutte, B., Ed.; Academic Press, Inc.  San Diego, CA, 1995; pp 93−169.

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