1. Department of Pharmacognosy, Department of Pharmacology and Toxicology, and Department of Pharmaceutical Chemistry, Computer Aided Molecular Design Group, Institute of Pharmacy, Leopold-Franzens University of Innsbruck, A-6020 Innsbruck, Austria, and Inte:Ligand GmbH, Software-Engineering and Consulting, Clemens Maria Hofbauergasse 6, A-2344 Maria Enzersdorf, Austria