Minor Groove Binders and Drugs Targeting Proteins Cover Complementary Regions in Chemical Shape Space-Reference-Cited by-同舟云学术

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Minor Groove Binders and Drugs Targeting Proteins Cover Complementary Regions in Chemical Shape Space

Published:2011-08-26 Issue:9 Volume:51 Page:2223-2232
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Fuchs Julian E.¹,Spitzer Gudrun M.¹,Javed Ameera¹,Biela Adam²,Kreutz Christoph¹,Wellenzohn Bernd³,Liedl Klaus R.¹

Affiliation:

1. Faculty of Chemistry and Pharmacy, University of Innsbruck, Innrain 52c, A-6020 Innsbruck, Austria

2. Department of Pharmaceutical Chemistry, Philipps University Marburg, Marbacher Weg 6, D-35032 Marburg, Germany

3. Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Strasse 65, D-88397 Biberach/Riss, Germany

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ci200237c

Reference71 articles.

1. Regulation of gene expression by small molecules

2. DNA minor-groove recognition by small molecules (up to 2000)

3. Minimization of a Protein−DNA Dimerizer

4. Therapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificities

5. Recognition of the DNA minor groove by pyrrole-imidazole polyamides

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