1. Morinaga Institute of Biological Science Inc., 2-1-16 Sachiura, Kanazawa-ku, Yokohama 236-0003, Japan; National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501 Japan; and The Second Teaching Hospital, Fujita Health University, 3-6-10 Otobashi, Nakagawa-ku, Nagoya 454-8509, Japan